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Home » Anti Inflammatory » Mobic
Mobic
Brand Names: Mobic, Movalis, Meloxicam, Melox, Recoxa, Mobicox, Metacam, Tenaron
Generic Name: Meloxicam
Manufacturer: Boehringer Ingelheim
Composition
1 tablet contains 7.5 mg or 15 mg
4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyI)-2H-1, 2-benzothiazine-3-carboxamide-1,
1-dioxide (= meloxicam)
Properties
MOBIC is a non-steroidal anti-inflammatory drug (NSAID) of the enolic acid class, which has shown anti- inflammatory, analgesic and antipyretic properties in animals. MOBIC showed potent anti-inflammatory activity in all standard models of inflammation. A common mechanism for the above effects may exist in the ability of MOBIC to inhibit the biosynthesis of prostaglandins, known mediators of inflammation. Comparison of the ulcerogenic dose and the anti-inflammatory effective dose in the rat adjuvant arthritis model confirmed a superior therapeutic margin in animals over standard NSAIDs. In vivo, MOBIC inhibited prostaglandin biosynthesis more potently at the site of inflammation than in the gastric mucosa or the kidney.
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